GLP-1: A New Path in the Treatment of Binge Eating Disorder

As a physician, I have seen firsthand the devastating impact of Binge Eating Disorder (BED) on my patients. It’s not just about weight or uncontrolled eating; it’s an internal struggle that brings guilt, anxiety, and a feeling of losing control. But in recent years, a new treatment has emerged as a beacon of hope: GLP-1 receptor agonists.

What Is GLP-1 and How Can It Help?

Glucagon-like peptide-1 (GLP-1) is a hormone that our body naturally produces, playing a key role in blood sugar regulation and appetite control. Initially, GLP-1-based medications like semaglutide (Ozempic, Wegovy) and liraglutide (Saxenda, Victoza), Tirzepatide, (Mounjaro and Zepbound) were developed initially to treat type 2 diabetes, and later on became approved to manage overweight and obesity.

However, researchers soon discovered that these drugs also help regulate food cravings and reduce compulsive eating.

My Experience with Patients Using GLP-1

I have worked with several patients who have incorporated GLP-1 into their treatment for BED. The difference they experience is remarkable:

✅ Fewer binge episodes and a greater sense of control over their eating habits.

✅ Reduced emotional hunger, as these medications affect the brain’s reward system.

✅ Gradual weight loss, improving both metabolic health and self-esteem.

But, I always emphasize that these medications are not a magic solution. Success comes from combining them with cognitive behavioral therapy, nutritional education, and lifestyle changes.

What Science Says About GLP-1 and BED

It’s not just my clinical experience—scientific evidence supports the use of GLP-1 in treating BED. A study published in Obesity Science & Practice found that liraglutide significantly reduced binge-eating episodes in patients with BED and bulimia nervosa (Wiley Online Library).

Another recent study published in PubMed showed that semaglutide not only helps with weight loss but also improves impulse control in people with BED (PubMed).

Is GLP-1 Right for You?

If you struggle with BED and have tried other treatments without success, GLP-1 could be an option to consider. However, it’s essential to talk to a doctor to evaluate whether it’s the right fit for you, as these medications can have side effects such as nausea or digestive changes.

The most important thing to remember is that you are not alone in this battle. There are tools and treatments available to help you regain control and improve your quality of life.

If you have questions or want to explore more about this treatment, I am here to help. It’s not just about losing weight—it’s about healing your relationship with food and yourself.

Dr. Dina Peralta

References

1. Richards J, Bang N, Ratliff EL, Paszkowiak MA, Khorgami Z, Khalsa SS, Simmons WK. Successful treatment of binge eating disorder with the GLP-1 agonist semaglutide: A retrospective cohort study. Obes Pillars. 2023 Jul 20;7:100080. doi: 10.1016/j.obpill.2023.100080. PMID: 37990682; PMCID: PMC10661993. (Link)

      2. Aoun L, Almardini S, Saliba F, Haddadin F, Mourad O, Jdaidani J, Morcos Z, Al Saidi I, Bou Sanayeh E, Saliba S, Almardini M, Zaidan J. GLP-1 receptor agonists: A novel pharmacotherapy for binge eating (Binge eating disorder and bulimia nervosa)? A systematic review. J Clin Transl Endocrinol. 2024 Feb 29;35:100333. doi: 10.1016/j.jcte.2024.100333. PMID: 38449772; PMCID: PMC10915596. 🔗 Link